Product Description
5-Nitroindole is a hydrophobic aromatic compound, and can be used as a universal base analog in oligonucleotides. Incorporation of universal bases into oligos is desirable in cases when either imprecise or random base-pairing is required, and the resulting “mis-matched” complements need to be stable. 5-Nitroindole does not discriminate between the four natural nucleotide bases in duplex formation. Substitution of this chemical as a universal base is less destabilizing towards the ends of oligos than towards the center. Substitutions at, or within eight bases of, the 3’-end produce primers that generally are ineffective at priming.

Product Details:
  • PubChem CID : 22523
  • Chemical Names : 5-Nitroindole; 6146-52-7; 5-Nitro-1H-indole; 1H-Indole, 5-nitro-; INDOLE, 5-NITRO-; UNII-O2BHX6EDBN
  • Molecular Formula : C8H6N2O2
  • Molecular Weight : 162.148 g/mol
  • IUPAC Name : 5-nitro-1~{H}-indole
  • CAS No : 6146-52-7
  • EC Number : 228-153-0
  • Monoisotopic Mass : 162.043 g/mol
  • Exact Mass : 162.043 g/mol
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