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Ondansetron

Ondansetron
Ondansetron
Product Description
Ondansetron is a serotonin 5-HT3 receptor antagonist which is prescribed for treatment of vomiting & nausea caused due to chemotherapy. It can be formulated in tablet or IV injection form. This compound has chemical formula C18H19N3O with molar mass of 293.4 g/mol. With protein binding ability of 70 to76%, it gets metabolized in liver by CYP3A4, CYP1A2, & CYP2D6 enzymes. This medicinal compound also shows effectiveness in gastroenteritis. Ondansetron works by blocking release of serotonin which is synthesized in response to chemotherapy agents that stimulate vagal afferents. It has bioavailability of around 60% with elimination half life of 5.7 hours.
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